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The most basic strategy to solve a Sudoku puzzle is to first write down, in each empty cell, all possible entries that will not contradict the One Rule with respect to the given cells. If a cell ends up having only one possible entry, it is a "forced" entry that you should fill in.
The 45 Rule\n\n An essential Killer Sudoku solving technique is the "45 rule". This uses the fact that every row, column and block must contain each of the numbers 1 to 9 once. Therefore, the total of all numbers in one row, column or block will always be 45.